SCHEMBL15433440

SCHEMBL15433440

CC/C(F)=C(\F)c1ccc(-c2ccc(C3COC(c4cc(F)c(C(F)(F)F)c(F)c4)OC3)cc2)c(F)c1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FASN P49327 1/20 0.36
CYP3A4 P08684 3/20 0.35
CYP2C9 P11712 2/20 0.35
APP P05067 2/20 0.33
RARB P10826 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
P2RY14 Q15391 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433439 0.81
SCHEMBL15433223 0.79
SCHEMBL15433220 0.74 CYP3A4 (0.31) CYP3A4CYP2C9CYP2C19
SCHEMBL15433215 0.74 KIF11 (0.39) FASNAPPRARB
SCHEMBL15433429 0.73 KIF11 (0.38) APPRARB
SCHEMBL15433583 0.73 PPARD (0.30)
SCHEMBL15433582 0.72
SCHEMBL15433435 0.71 AKR1C3 (0.33) APPRARB
SCHEMBL15433733 0.70 FFAR4 (0.32)
SCHEMBL15433181 0.70 RARB (0.40) FASNCYP3A4CYP2C9APPRARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed