SCHEMBL15433457

SCHEMBL15433457

CCO/C(F)=C(\F)c1ccc(C2CCC(c3ccc(-c4cc(F)c(OC(F)(F)F)c(F)c4)c(F)c3)CC2)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FASN P49327 1/20 0.33
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433216 0.79 GRM2 (0.32) CYP3A4CYP2C9
SCHEMBL15433695 0.76 FFAR4 (0.35)
SCHEMBL10014269 0.75 FASN (0.39) FASNCYP3A4CYP2C9
SCHEMBL15433458 0.74 SLC9A1 (0.31)
SCHEMBL17175206 0.74 CYP3A4 (0.32) FASNCYP3A4CYP2C9
SCHEMBL14946006 0.73 CYP2C9 (0.35) FASNCYP3A4CYP2C9
SCHEMBL15433436 0.73 FASN (0.36) FASNCYP3A4CYP2C9
SCHEMBL15433460 0.73
SCHEMBL17175207 0.73 CYP2C9 (0.37) FASNCYP3A4CYP2C9
SCHEMBL13453388 0.73 CYP3A4 (0.33) CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed