SCHEMBL15433458

SCHEMBL15433458

CCC/C(F)=C(\F)c1ccc(-c2ccc(C3CCC(c4cc(F)c(OC(F)(F)F)c(F)c4)CC3)c(F)c2)cc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 1/20 0.31
DHODH Q02127 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433231 0.79
SCHEMBL15433442 0.78 CYP2C9 (0.35) SLC9A1
SCHEMBL15433229 0.76 ALDH1A1 (0.34) SLC9A1FFAR4
SCHEMBL15433460 0.76
SCHEMBL15433745 0.76 OPRL1 (0.35) FFAR4
SCHEMBL15433415 0.75 HPGD (0.32) SLC9A1
SCHEMBL15433655 0.75 KIF11 (0.30)
SCHEMBL15433352 0.75 FFAR1 (0.31) FFAR4
SCHEMBL15433284 0.75 GSK3B (0.34) DHODHFFAR4
SCHEMBL15433457 0.74 FASN (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed