Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15411539 | 0.89 | ALDH1A1 (0.43) | ADORA2AALDH1A1PIK3CGPIK3CDSMN1; SMN2 | |
| SCHEMBL15411537 | 0.89 | ALDH1A1 (0.43) | ADORA2AALDH1A1PIK3CGPIK3CDSMN1; SMN2 | |
| SCHEMBL15411158 | 0.88 | ADORA2A (0.45) | ADORA2AALDH1A1PIK3CGPIK3CDSMN1; SMN2 | |
| SCHEMBL15411630 | 0.86 | ADORA2A (0.44) | ADORA2AALDH1A1PIK3CGPIK3CDSMN1; SMN2 | |
| SCHEMBL15411350 | 0.84 | ADORA2A (0.42) | ADORA2AALDH1A1PIK3CGPIK3CDSMN1; SMN2 | |
| SCHEMBL15410377 | 0.82 | ADORA2A (0.45) | ADORA2AALDH1A1PIK3CGPIK3CDSMN1; SMN2 | |
| SCHEMBL15411621 | 0.82 | ADORA2A (0.39) | ADORA2AALDH1A1PIK3CGPIK3CDSMN1; SMN2 | |
| SCHEMBL15411069 | 0.74 | EGLN2 (0.42) | ADORA2APIK3CGPIK3CDMC4RTOP2A | |
| SCHEMBL18076251 | 0.73 | MALT1 (0.40) | ADORA2AALDH1A1PIK3CGPIK3CDTOP2A | |
| SCHEMBL15410874 | 0.73 | EGLN2 (0.40) | ADORA2AALDH1A1MC4RTOP2AFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014009425-A1 | INHIBITION OF ENZYMES | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-01-16 | — | — | WO | disclosed |