Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15411537 | 1.00 | ALDH1A1 (0.43) | ALDH1A1GAAADORA2APIK3CGPIK3CD | |
| SCHEMBL15434244 | 0.89 | ADORA2A (0.40) | ALDH1A1ADORA2APIK3CGPIK3CDMC4R | |
| SCHEMBL15411158 | 0.87 | ADORA2A (0.45) | ALDH1A1ADORA2APIK3CGPIK3CDMC4R | |
| SCHEMBL15411621 | 0.86 | ADORA2A (0.39) | ALDH1A1ADORA2APIK3CGPIK3CDRAD52 | |
| SCHEMBL15411630 | 0.85 | ADORA2A (0.44) | ALDH1A1ADORA2APIK3CGPIK3CDMC4R | |
| SCHEMBL15411350 | 0.84 | ADORA2A (0.42) | ALDH1A1ADORA2APIK3CGPIK3CDMC4R | |
| SCHEMBL15410377 | 0.81 | ADORA2A (0.45) | ALDH1A1ADORA2APIK3CGPIK3CDMC4R | |
| SCHEMBL15411069 | 0.73 | EGLN2 (0.42) | ADORA2APIK3CGPIK3CDMC4RTOP2A | |
| SCHEMBL15410874 | 0.72 | EGLN2 (0.40) | ALDH1A1ADORA2AMC4RTOP2AFYN | |
| SCHEMBL18076251 | 0.71 | MALT1 (0.40) | ALDH1A1ADORA2APIK3CGPIK3CDTOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872509-B1 | INHIBITION OF ENZYMES | CHIESI FARMA SPA (IT) | 2016-09-14 | — | — | EP | disclosed |
| US-9199984-B2 | Inhibition of enzymes | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-12-01 | — | — | US | disclosed |
| EP-2872509-A1 | INHIBITION OF ENZYMES | Chiesi Farmaceutici S.p.A. (IT) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014009425-A1 | INHIBITION OF ENZYMES | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-01-16 | — | — | WO | disclosed |
| US-20140018345-A1 | INHIBITION OF ENZYMES | CHIESI FARMACEUTICI S.P.A (IT) | 2014-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018345-A1 | INHIBITION OF ENZYMES | SERPINB1, ELANE, MPO | ALDH1A1 134/4885GAA 155/4885ADORA2A 1511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.