SCHEMBL15434263

SCHEMBL15434263

CC1(C)c2ccccc2-c2ccc3c(sc4c5c(ccc43)-c3ccc(-c4ccccc4)cc3C5(C)C)c21

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 16/20 0.43
PGR P06401 2/20 0.35
RARA P10276 1/20 0.34
RARB P10826 1/20 0.34
RARG P13631 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15434188 0.87 LIMK1 (0.38) PDK2
SCHEMBL17057191 0.85 PDK2 (0.42) PDK2PGR
SCHEMBL19076984 0.83 F9 (0.32) PDK2
SCHEMBL17944761 0.83 ALOX5 (0.39) PDK2PGRRARARARBRARG
SCHEMBL21791209 0.82
SCHEMBL10018876 0.82 ALOX5 (0.39) PDK2PGRRARARARBRARG
SCHEMBL15434264 0.81 KDM4E (0.32)
SCHEMBL22057508 0.81 PDK2 (0.31) PDK2
SCHEMBL14101650 0.81 PDK2 (0.43) PDK2PGRRARARARBRARG
SCHEMBL22057419 0.81 ABCB1 (0.34) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014010910-A1 COMPOUND, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산하이메탈(주) (KR) 2014-01-16 WO disclosed