Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 5/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15435287 | 0.98 | FFAR1 (0.48) | FFAR1NPC1RAB9AMAOAMAOB | |
| SCHEMBL15400449 | 0.95 | MAOA (0.51) | FFAR1NPC1RAB9AMAOAMAOB | |
| SCHEMBL29263961 | 0.91 | NPC1 (0.60) | FFAR1NPC1RAB9AMAOAMAOB | |
| SCHEMBL7075105 | 0.86 | NPC1 (0.53) | FFAR1NPC1RAB9AMAOAMAOB | |
| SCHEMBL27503820 | 0.82 | FFAR1 (0.49) | FFAR1MAOAMAOBPLA2G4BNAAA | |
| SCHEMBL519206 | 0.81 | MAOB (0.58) | RAB9AMAOAMAOB | |
| SCHEMBL13862125 | 0.81 | MAOB (0.43) | NPC1RAB9AMAOAMAOBDRD4 | |
| SCHEMBL31552396 | 0.80 | ALDH1A1 (0.48) | NPC1MAOB | |
| Hydrochloric Acid SCHEMBL4716320 | 0.80 | MAOB (0.56) | RAB9AMAOAMAOB | |
| SCHEMBL8522890 | 0.79 | FFAR1 (0.57) | FFAR1PLA2G4BS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687507-B1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2016-03-09 | — | — | EP | disclosed |
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| EP-2687507-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | Taisho Pharmaceutical Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |