Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOGAT2 | Q3SYC2 | 10/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.40 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15435408 | 0.90 | MOGAT2 (0.57) | MOGAT2ABCB1MLNRDRD2DRD3 | |
| SCHEMBL16715484 | 0.89 | AR (0.55) | MOGAT2PRMT5WDR77MEN1POLB | |
| SCHEMBL15435191 | 0.85 | MOGAT2 (0.75) | MOGAT2ABCB1MLNRDRD2DRD3 | |
| SCHEMBL15435427 | 0.80 | MOGAT2 (0.63) | MOGAT2ABCB1HTR6MEN1KMT2A | |
| SCHEMBL16715485 | 0.78 | AR (0.54) | MOGAT2POLB | |
| SCHEMBL15435035 | 0.77 | MOGAT2 (0.63) | MOGAT2ABCB1MLNRDRD2DRD3 | |
| SCHEMBL16715481 | 0.76 | MOGAT2 (0.68) | MOGAT2ABCB1 | |
| SCHEMBL15435247 | 0.73 | MOGAT2 (0.69) | MOGAT2ABCB1MEN1KMT2A | |
| SCHEMBL15435261 | 0.73 | MOGAT2 (0.81) | MOGAT2 | |
| SCHEMBL15435356 | 0.73 | MOGAT2 (0.78) | MOGAT2DRD2DRD3HTR6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687507-B1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2016-03-09 | — | — | EP | disclosed |
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| EP-2687507-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | Taisho Pharmaceutical Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |