Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1694606 | 0.83 | CHRNA7 (0.38) | IDH1 | |
| SCHEMBL1962579 | 0.82 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL1789240 | 0.82 | TRPV4 (0.48) | — | |
| SCHEMBL24618209 | 0.82 | IDH1 (0.34) | IDH1 | |
| SCHEMBL25575002 | 0.80 | IDH1 (0.34) | IDH1 | |
| SCHEMBL14846920 | 0.80 | PDE2A (0.40) | IDH1 | |
| SCHEMBL2692329 | 0.80 | PDE2A (0.40) | IDH1 | |
| SCHEMBL12868052 | 0.80 | UGT2B7 (0.34) | IDH1 | |
| SCHEMBL21789264 | 0.80 | IDH1 (0.34) | IDH1 | |
| SCHEMBL12299466 | 0.78 | PDE4A (0.34) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687507-B1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2016-03-09 | — | — | EP | disclosed |
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| US-9035059-B2 | Nitrogen-containing condensed heterocyclic compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-19 | — | — | US | disclosed |
| EP-2687507-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | Taisho Pharmaceutical Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |