Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.48 |
| ▸ | PDE2A | O00408 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2609310 | 0.84 | TRPV4 (0.52) | TRPV4PDE2AP2RX7KDM5BGPR139 | |
| SCHEMBL15435342 | 0.82 | IDH1 (0.34) | — | |
| SCHEMBL15702107 | 0.82 | TRPV4 (0.50) | TRPV4PDE2AP2RX7DAO | |
| SCHEMBL1962579 | 0.81 | SMN1; SMN2 (0.32) | P2RX7MLYCD | |
| SCHEMBL367869 | 0.81 | TRPV4 (0.48) | TRPV4PDE2AP2RX7KDM5BGPR139 | |
| SCHEMBL19773439 | 0.81 | TRPV4 (0.48) | TRPV4PDE2AP2RX7KDM5BGPR139 | |
| SCHEMBL485040 | 0.81 | TRPV4 (0.48) | TRPV4PDE2AP2RX7GPR139NR1I2 | |
| SCHEMBL998305 | 0.81 | TRPV4 (0.48) | TRPV4PDE2AP2RX7KDM5BGPR139 | |
| SCHEMBL21346253 | 0.81 | TRPV4 (0.48) | TRPV4PDE2AP2RX7KDM5BGPR139 | |
| SCHEMBL347477 | 0.81 | TRPV4 (0.48) | TRPV4PDE2AP2RX7KDM5BGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240287070-A1 | FUSED HETEROCYCLIC DERIVATIVES | JOHNSON & JOHNSON (CHINA) INVESTMENT LTD. (CN) | 2024-08-29 | — | — | US | disclosed |
| US-20240279227-A1 | FUSED HETEROCYCLIC DERIVATIVES | JANSSEN BIOTECH, INC. | 2024-08-22 | — | — | US | disclosed |
| CN-117881661-A | Condensed heterocyclic derivative | 杨森科学爱尔兰无限公司 | 2024-04-12 | — | — | CN | disclosed |
| EP-4347036-A1 | FUSED HETEROCYCLIC DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2024-04-10 | — | — | EP | disclosed |
| EP-4347590-A1 | FUSED HETEROCYCLIC DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2024-04-10 | — | — | EP | disclosed |
| EP-3455224-B1 | SUBSTITUTED 5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRIDINE-3(2H)-ONES AND 2,5,6,7-TETRAHYDRO-3H-PYRROLO[2,1-C][1,2,4]TRIAZOL-3-ONES, AND USE THEREOF | BAYER AG (DE) | 2024-03-27 | — | — | EP | disclosed |
| CN-117715909-A | Condensed heterocyclic derivative | 杨森科学爱尔兰无限公司 | 2024-03-15 | — | — | CN | disclosed |
| WO-2022253259-A1 | FUSED HETEROCYCLIC DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2022-12-08 | — | — | WO | disclosed |
| WO-2022253255-A1 | FUSED HETEROCYCLIC DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2022-12-08 | — | — | WO | disclosed |
| WO-2022253255-A1 | FUSED HETEROCYCLIC DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2022-12-08 | — | — | WO | disclosed |
| US-7705154-B2 | Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines | DOW AGROSCIENCES LLC (US) | 2010-04-27 | — | — | US | disclosed |
| US-7705154-B2 | Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines | DOW AGROSCIENCES LLC (US) | 2010-04-27 | — | — | US | disclosed |
| EP-2086936-A2 | PROCESS FOR THE PREPARATION OF 2-SUBSTITUTED-5-(1-ALKYLTHIO)ALKYLPYRIDINES | Dow AgroSciences LLC (US) | 2009-08-12 | — | — | EP | disclosed |
| WO-2009025397-A1 | FLUORINE-CONTAINING ORGANOSULFUR COMPOUND AND PESTICIDAL COMPOSITION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-02-26 | — | — | WO | disclosed |
| WO-2009025397-A1 | FLUORINE-CONTAINING ORGANOSULFUR COMPOUND AND PESTICIDAL COMPOSITION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-02-26 | — | — | WO | disclosed |
| CN-101248050-A | Organic compounds | INTRA CELLULAR THERAPIES INC (US) | 2008-08-20 | — | — | CN | disclosed |
| WO-2008066558-A2 | PROCESS FOR THE PREPARATION OF 2-SUBSTITUTED-5-(1-ALKYLTHIO)ALKYLPYRIDINES | DOW AGROSCIENCES LLC (US) | 2008-06-05 | — | — | WO | disclosed |
| US-20080132705-A1 | Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines | CORTEVA AGRISCIENCE LLC | 2008-06-05 | — | — | US | disclosed |
| US-20080132705-A1 | Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines | CORTEVA AGRISCIENCE LLC | 2008-06-05 | — | — | US | disclosed |
| CN-1918165-A | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL MYERS SQUIBB CO (US) | 2007-02-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240287070-A1 | FUSED HETEROCYCLIC DERIVATIVES | HAVCR2, HCCS, GOT2 | TRPV4 4510/4885PDE2A 3603/4885P2RX7 2462/4885 |
| US-20080132705-A1 | Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines | AGPS, TPMT, PFAS | TRPV4 1720/4885PDE2A 716/4885P2RX7 1897/4885 |
| US-20240279227-A1 | FUSED HETEROCYCLIC DERIVATIVES | HAVCR2, HCCS, GOT2 | TRPV4 4510/4885PDE2A 3603/4885P2RX7 2462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.