Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12525523 | 0.87 | REN (0.48) | RENKMT2ANR3C1ALDH1A1 | |
| SCHEMBL12525512 | 0.86 | REN (0.38) | RENKMT2ANR3C1MEN1RET | |
| SCHEMBL12525840 | 0.77 | REN (0.47) | RENNR3C1 | |
| SCHEMBL13132282 | 0.76 | REN (0.38) | RENKMT2ANR3C1MEN1RET | |
| SCHEMBL16471650 | 0.75 | REN (0.38) | RENKMT2ANR3C1ALDH1A1 | |
| SCHEMBL15417952 | 0.74 | ALDH1A1 (0.33) | RENKMT2ANR3C1ALDH1A1 | |
| SCHEMBL15417977 | 0.72 | REN (0.40) | RENRETL3MBTL1 | |
| SCHEMBL13132275 | 0.67 | REN (0.36) | RENKMT2ANR3C1RET | |
| SCHEMBL13131392 | 0.66 | REN (0.35) | RENKMT2ANR3C1 | |
| SCHEMBL13131395 | 0.66 | REN (0.45) | RENKMT2ANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687518-A1 | NITROGEN-CONTAINING SATURATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2014-01-22 | — | — | EP | disclosed |