SCHEMBL15435756

SCHEMBL15435756

Cc1ccccc1-n1c2ccccc2c2cc(-c3ccc4c(c3)c3ccccc3n4-c3ccc(-n4c5ccccc5c5ccccc54)cc3)ccc21

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 2/20 0.46
ATM Q13315 1/20 0.46
TSHR P16473 1/20 0.40
ALDH1A1 P00352 4/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
PTGER4 P35408 1/20 0.37
RAB9A P51151 1/20 0.36
LMNA P02545 1/20 0.36
NPY5R Q15761 1/20 0.36
TSPO P30536 1/20 0.36
HDAC4 P56524 1/20 0.36
ALKBH5 Q6P6C2 1/20 0.36
FTO Q9C0B1 1/20 0.36
EDNRA P25101 1/20 0.34
NOTUM Q6P988 1/20 0.34
KLK7 P49862 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL261904 0.92 L3MBTL1 (0.42) L3MBTL1KDM4EATMTSHRALDH1A1
SCHEMBL262385 0.92 L3MBTL1 (0.42) L3MBTL1KDM4EATMTSHRALDH1A1
SCHEMBL15435797 0.91 L3MBTL1 (0.43) L3MBTL1KDM4EATMTSHRALDH1A1
SCHEMBL13238039 0.91 MAPT (0.39) L3MBTL1KDM4EATMTSHRALDH1A1
SCHEMBL16726758 0.90 PTGER4 (0.41) L3MBTL1KDM4EATMTSHRALDH1A1
SCHEMBL21037653 0.89 TSPO (0.45) L3MBTL1KDM4EATMTSHRALDH1A1
SCHEMBL262390 0.88 KDM4E (0.39) L3MBTL1KDM4EATMALDH1A1PTGER4
SCHEMBL24666894 0.87 KDM4E (0.42) L3MBTL1KDM4EATMTSHRALDH1A1
SCHEMBL13238022 0.87 L3MBTL1 (0.44) L3MBTL1KDM4EATMTSHRALDH1A1
SCHEMBL15306420 0.86 L3MBTL1 (0.43) L3MBTL1KDM4EATMTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2688120-B1 LIGHT-EMITTING ELEMENT MATERIAL AND LIGHT-EMITTING ELEMENT TORAY INDUSTRIES (JP) 2017-08-23 EP disclosed
US-9537107-B2 Light emitting device material and light emitting device TORAY INDUSTRIES, INC. (JP) 2017-01-03 US disclosed
EP-2688120-A1 LIGHT-EMITTING ELEMENT MATERIAL AND LIGHT-EMITTING ELEMENT Toray Industries, Inc. (JP) 2014-01-22 EP disclosed