Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18674704 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTFAAHSMN1; SMN2SLC6A5 | |
| SCHEMBL23376623 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTFAAHSMN1; SMN2SLC6A5 | |
| SCHEMBL26644372 | 0.87 | FAAH (0.56) | ALDH1A1MAPTFAAHSMN1; SMN2SLC6A5 | |
| SCHEMBL9550539 | 0.84 | FAAH (0.66) | ALDH1A1MAPTFAAHSMN1; SMN2SLC6A5 | |
| SCHEMBL15602675 | 0.84 | FAAH (0.66) | ALDH1A1MAPTFAAHSMN1; SMN2SLC6A5 | |
| SCHEMBL15623807 | 0.82 | FAAH (0.69) | ALDH1A1MAPTFAAHSMN1; SMN2SLC6A5 | |
| SCHEMBL30838577 | 0.82 | FAAH (0.69) | ALDH1A1MAPTFAAHSMN1; SMN2SLC6A5 | |
| SCHEMBL4572566 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MAPTFAAHSMN1; SMN2SLC6A5 | |
| SCHEMBL30838580 | 0.82 | FAAH (0.69) | ALDH1A1MAPTFAAHSMN1; SMN2SLC6A5 | |
| SCHEMBL2269347 | 0.82 | FAAH (0.59) | ALDH1A1MAPTFAAHSMN1; SMN2SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076276-B1 | SOL-GEL MATERIALS FOR CELLULAR MODULATION | PURDUE RESEARCH FOUNDATION (US) | 2014-01-22 | — | — | EP | disclosed |