Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15435914 | 0.88 | HRH3 (0.34) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL1525497 | 0.85 | CYP2J2 (0.33) | MEN1KMT2ADRD2HTR2AHRH1 | |
| SCHEMBL2076961 | 0.84 | MAPK1 (0.37) | KDM4EKMT2AALDH1A1GAA | |
| SCHEMBL16898773 | 0.83 | MEN1 (0.32) | KDM4EMEN1KMT2AHRH3 | |
| SCHEMBL3009489 | 0.78 | CYP2J2 (0.32) | HRH3DRD2DRD4HTR2AHRH1 | |
| SCHEMBL28780771 | 0.78 | DRD3 (0.33) | SMN1; SMN2CYP2D6DRD2DRD4DRD3 | |
| SCHEMBL3657529 | 0.78 | CYP2J2 (0.32) | HTR2AHRH1DRD3HTR2BKCNH2 | |
| SCHEMBL3504744 | 0.77 | KDM2B (0.30) | — | |
| SCHEMBL3572416 | 0.77 | ALOX15 (0.36) | DRD3 | |
| SCHEMBL16099560 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014016202-A1 | METHODS FOR CATALYTIC ALKYLATION OF NUCLEIC ACIDS | UNIVERSITÄT BASEL (CH) | 2014-01-30 | — | — | WO | disclosed |
| EP-2689847-A1 | Methods for catalytic alkylation of nucleic acids | Universität Basel (CH) | 2014-01-29 | — | — | EP | disclosed |