Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15435944 | 0.88 | HTR1A (0.35) | HRH3MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL3657529 | 0.85 | CYP2J2 (0.32) | LMNA | |
| SCHEMBL15435917 | 0.85 | MEN1 (0.44) | HRH3MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL16099560 | 0.85 | — | — | |
| SCHEMBL16898773 | 0.82 | MEN1 (0.32) | HRH3MEN1KMT2AKDM4E | |
| SCHEMBL1525497 | 0.78 | CYP2J2 (0.33) | MEN1KMT2ALMNAPOLBCYP2C19 | |
| SCHEMBL26101702 | 0.78 | HRH3 (0.41) | HRH3KDM4ELMNASMN1; SMN2POLB | |
| SCHEMBL2076961 | 0.78 | MAPK1 (0.37) | KMT2AKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL15435926 | 0.77 | MEN1 (0.39) | HRH3MEN1KMT2AKDM4EGAA | |
| SCHEMBL28780771 | 0.77 | DRD3 (0.33) | SMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014016202-A1 | METHODS FOR CATALYTIC ALKYLATION OF NUCLEIC ACIDS | UNIVERSITÄT BASEL (CH) | 2014-01-30 | — | — | WO | disclosed |
| EP-2689847-A1 | Methods for catalytic alkylation of nucleic acids | Universität Basel (CH) | 2014-01-29 | — | — | EP | disclosed |