SCHEMBL15435978

SCHEMBL15435978

c1ccc(-n2c3ccccc3c3ccc(-c4ccc5c6ccccc6n(-c6cccc(-n7c8ccccc8c8ccccc87)c6)c5c4)cc32)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.64
KDM4E B2RXH2 1/20 0.64
ATM Q13315 1/20 0.64
KMT2A Q03164 4/20 0.41
IL1R1 P14778 1/20 0.41
HDAC4 P56524 1/20 0.40
ALDH1A1 P00352 4/20 0.40
MEN1 O00255 3/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
MAPK8 P45983 2/20 0.37
MAPK1 P28482 1/20 0.37
PGR P06401 1/20 0.37
MAPK9 P45984 1/20 0.36
GAA P10253 2/20 0.36
KDR P35968 1/20 0.36
LMNA P02545 1/20 0.36
FOLH1 Q04609 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15435968 0.95 L3MBTL1 (0.58) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL18352545 0.95 L3MBTL1 (0.58) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL19238811 0.95 L3MBTL1 (0.62) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL13309232 0.95 L3MBTL1 (0.57) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL15850742 0.94 L3MBTL1 (0.72) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL16410042 0.94 L3MBTL1 (0.72) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL23370595 0.93 ATM (0.60) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL16901146 0.93 ATM (0.60) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL19238839 0.93 L3MBTL1 (0.60) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL16171542 0.93 L3MBTL1 (0.64) L3MBTL1KDM4EATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2688120-B1 LIGHT-EMITTING ELEMENT MATERIAL AND LIGHT-EMITTING ELEMENT TORAY INDUSTRIES (JP) 2017-08-23 EP disclosed
US-9537107-B2 Light emitting device material and light emitting device TORAY INDUSTRIES, INC. (JP) 2017-01-03 US disclosed
EP-2688120-A1 LIGHT-EMITTING ELEMENT MATERIAL AND LIGHT-EMITTING ELEMENT Toray Industries, Inc. (JP) 2014-01-22 EP disclosed