SCHEMBL15435968

SCHEMBL15435968

c1ccc(-n2c3ccccc3c3ccc(-c4ccc5c(c4)c4ccccc4n5-c4cccc(-n5c6ccccc6c6ccccc65)c4)cc32)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.58
KDM4E B2RXH2 1/20 0.58
ATM Q13315 1/20 0.58
PTGER4 P35408 1/20 0.38
KMT2A Q03164 3/20 0.38
IL1R1 P14778 1/20 0.38
TSPO P30536 1/20 0.37
HDAC4 P56524 1/20 0.37
MEN1 O00255 2/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
EDNRB P24530 1/20 0.35
EDNRA P25101 1/20 0.35
MAPK8 P45983 2/20 0.35
MAPK1 P28482 1/20 0.34
PGR P06401 1/20 0.34
GAA P10253 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18352545 1.00 L3MBTL1 (0.58) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL23187320 0.97 L3MBTL1 (0.55) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL25941112 0.95 L3MBTL1 (0.53) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL20780384 0.95 L3MBTL1 (0.56) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL21747140 0.95 L3MBTL1 (0.56) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL27050250 0.95 L3MBTL1 (0.56) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL20781094 0.95 L3MBTL1 (0.56) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL20780383 0.95 L3MBTL1 (0.56) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL15625363 0.95 L3MBTL1 (0.56) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL15435799 0.95 L3MBTL1 (0.64) L3MBTL1KDM4EATMPTGER4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 US disclosed
EP-2688120-B1 LIGHT-EMITTING ELEMENT MATERIAL AND LIGHT-EMITTING ELEMENT TORAY INDUSTRIES (JP) 2017-08-23 EP disclosed
US-9537107-B2 Light emitting device material and light emitting device TORAY INDUSTRIES, INC. (JP) 2017-01-03 US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
EP-2688120-A1 LIGHT-EMITTING ELEMENT MATERIAL AND LIGHT-EMITTING ELEMENT Toray Industries, Inc. (JP) 2014-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AOC2, AZI2, RER1 L3MBTL1 2484/4885KDM4E 2736/4885ATM 3725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.