Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | AGER | Q15109 | 3/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19583039 | 0.80 | CCR5 (0.44) | KDM4EAGERMTNR1ACCR5MEN1 | |
| SCHEMBL25699414 | 0.78 | DPP8 (0.38) | KDM4ECCR5MEN1KMT2AALDH1A1 | |
| SCHEMBL25573148 | 0.78 | DPP8 (0.38) | KDM4ECCR5MEN1KMT2AALDH1A1 | |
| SCHEMBL1543234 | 0.78 | MEN1 (0.40) | KDM4EAGERMTNR1ACCR5MEN1 | |
| SCHEMBL31629952 | 0.75 | CCR5 (0.46) | KDM4ECCR5MEN1KMT2AALDH1A1 | |
| SCHEMBL1963929 | 0.75 | CCR5 (0.41) | KDM4EAGERMTNR1ACCR5MEN1 | |
| SCHEMBL13734746 | 0.75 | TRPA1 (0.51) | KDM4EAGERCCR5MEN1KMT2A | |
| SCHEMBL29856880 | 0.75 | CCR5 (0.46) | KDM4ECCR5MEN1KMT2AALDH1A1 | |
| SCHEMBL27876478 | 0.75 | CCR5 (0.46) | KDM4ECCR5MEN1KMT2AALDH1A1 | |
| SCHEMBL14657441 | 0.75 | TRPA1 (0.51) | KDM4EAGERCCR5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307377-A1 | NICOTINAMIDE DERIVATIVES | Pfizer Limited (GB) | 2011-04-13 | — | — | EP | disclosed |