Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | RORA | P35398 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 1/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | SGK1 | O00141 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15437876 | 1.00 | SCN9A (0.39) | SCN9ANR3C2BRD4MAP2K4ALDH1A1 | |
| SCHEMBL15437378 | 0.91 | KIF11 (0.38) | BRD4HPGDRORCRORANR1H2 | |
| SCHEMBL15437499 | 0.89 | LPAR1 (0.42) | NR3C2RORCRORANR1H2NR1H3 | |
| SCHEMBL15437826 | 0.89 | LPAR1 (0.42) | NR3C2RORCRORANR1H2NR1H3 | |
| SCHEMBL15438023 | 0.88 | KIF11 (0.37) | BRD4RORCRORANR1H2NR1H3 | |
| SCHEMBL15437361 | 0.84 | RORC (0.38) | NR3C2BRD4MAP2K4ALDH1A1RORC | |
| SCHEMBL15437757 | 0.83 | MAPT (0.36) | SCN9ARORCRORANR1H2NR1H3 | |
| SCHEMBL15437669 | 0.82 | KIF11 (0.43) | BRD4RORCRORANR1H2NR1H3 | |
| SCHEMBL4032476 | 0.81 | LPAR1 (0.43) | ALDH1A1LPAR1LPAR2LPAR3FTO | |
| SCHEMBL15437817 | 0.81 | LPAR1 (0.41) | ALDH1A1RORCRORANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785442-B2 | Compound as antagonist of lysophosphatidic acid receptor, composition, and use thereof | CUREGENIX, INC. (CN) | 2014-07-22 | — | — | US | claimed |
| US-20140031353-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | CUREGENIX, INC. (CN) | 2014-01-30 | — | — | US | claimed |
| US-8785442-B2 | Compound as antagonist of lysophosphatidic acid receptor, composition, and use thereof | CUREGENIX, INC. (CN) | 2014-07-22 | — | — | US | disclosed |
| US-20140031353-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | CUREGENIX, INC. (CN) | 2014-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031353-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | LPAR1, LPAR2, LPAR5 | SCN9A 2398/4885NR3C2 919/4885BRD4 1846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.