Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
| ▸ | PRKCA | P17252 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | CA9 | Q16790 | 4/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20944781 | 0.99 | SNCA (0.66) | SNCAPTPN1PRKCACA2CA9 | |
| SCHEMBL15711514 | 0.99 | SNCA (0.66) | SNCAPTPN1PRKCACA2CA9 | |
| SCHEMBL546975 | 0.99 | SNCA (0.66) | SNCAPTPN1PRKCACA2CA9 | |
| SCHEMBL9942532 | 0.91 | SNCA (0.66) | SNCAPTPN1PRKCACA2CA9 | |
| SCHEMBL15711524 | 0.88 | LDHA (0.65) | SNCAPTPN1CA2CA9CA12 | |
| SCHEMBL546911 | 0.88 | LDHA (0.65) | SNCAPTPN1CA2CA9CA12 | |
| SCHEMBL30192596 | 0.88 | LDHA (0.65) | SNCAPTPN1CA2CA9CA12 | |
| SCHEMBL546910 | 0.88 | LDHA (0.65) | SNCAPTPN1CA2CA9CA12 | |
| SCHEMBL9942524 | 0.88 | SNCA (0.65) | SNCAPTPN1PRKCACA2CA9 | |
| SCHEMBL3986428 | 0.87 | GAA (0.65) | SNCAPRKCAGAATDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10233457-B2 | Inhibition of a xylosyltransferase to improve saccharification efficiency | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-03-19 | — | — | US | disclosed |
| US-20140033365-A1 | Inhibition of a Xylosyltransferase to Improve Saccharification Efficiency | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-01-30 | — | — | US | disclosed |