SCHEMBL546911

SCHEMBL546911

COc1cc(/C=C/C(=O)O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc(OC)c1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LDHA P00338 1/20 0.65
▸ SNCA P37840 1/20 0.62
▸ EPHX2 P34913 3/20 0.61
▸ PTGS1 P23219 2/20 0.56
▸ CA12 O43570 5/20 0.54
▸ CA9 Q16790 5/20 0.54
▸ CA1 P00915 4/20 0.54
▸ CA2 P00918 2/20 0.54
▸ TYR P14679 1/20 0.50
▸ ALOX5 P09917 1/20 0.50
▸ MET P08581 1/20 0.50
▸ PTPN1 P18031 1/20 0.49
▸ CYP1A2 P05177 1/20 0.49
▸ CYP3A4 P08684 1/20 0.49
▸ CYP2D6 P10635 1/20 0.49
▸ CYP2C9 P11712 1/20 0.49
▸ CYP2B6 P20813 1/20 0.49
▸ GAA P10253 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.48
▸ CA7 P43166 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15711524 1.00 LDHA (0.65) LDHASNCAEPHX2PTGS1CA12
SCHEMBL546910 1.00 LDHA (0.65) LDHASNCAEPHX2PTGS1CA12
SCHEMBL30192596 1.00 LDHA (0.65) LDHASNCAEPHX2PTGS1CA12
SCHEMBL9231443 0.95 LDHA (0.60) LDHASNCAEPHX2PTGS1CA12
SCHEMBL26485996 0.91 LDHA (0.58) LDHASNCAEPHX2PTGS1CA12
SCHEMBL30429113 0.91 LDHA (0.58) LDHASNCAEPHX2PTGS1CA12
SCHEMBL2928116 0.91 LDHA (0.58) LDHASNCAEPHX2PTGS1CA12
SCHEMBL15711514 0.89 SNCA (0.66) LDHASNCAEPHX2PTGS1CA12
SCHEMBL546975 0.89 SNCA (0.66) LDHASNCAEPHX2PTGS1CA12
SCHEMBL20944781 0.89 SNCA (0.66) LDHASNCAEPHX2PTGS1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 412 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108634-A1 HIGH MOLECULAR WEIGHT MULTI-ARM POLYMERS AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-23 — — US claimed
EP-4724117-A2 METHOD OF TREATING AN ARTICULAR CONDITION OR A CONDITION OF A BONY CANAL Ocular Therapeutix, Inc. (US) 2026-04-15 — — EP claimed
US-12599624-B2 Biodegradable lung sealants ETHICON, INC. (US) 2026-04-14 — — US claimed
EP-4580690-B1 BIODEGRADABLE LUNG SEALANTS ETHICON INC (US) 2026-03-18 — — EP claimed
US-20260035435-A1 APPROACHES FOR THE SELECTIVE DEPLETION OF PLA2R-SPECIFIC ANTIBODIES Astero BioPharma LLC (US) 2026-02-05 — — US claimed
EP-4683964-A2 POLY(ETHYLENE GLYCOL) BASED DENDRIMER-LIKE HYPERBRANCHED MACROMOLECULES, METHODS OF PREPARATION AND USE THEREOF Ocular Therapeutix, Inc. (US) 2026-01-28 — — EP claimed
EP-4676553-A1 MEDICAL SEALANTS Ethicon, Inc. (US) 2026-01-14 — — EP claimed
US-20250382348-A1 APPROACHES FOR THE SELECTIVE DEPLETION OF PLA2R-SPECIFIC ANTIBODIES Astero BioPharma LLC (US) 2025-12-18 — — US claimed
EP-4630058-A2 CHEMICAL TISSUE ABLATION WITH HYDROGEL MATRIX AND CORRESPONDING MEDICAL APPLICATIONS Pramand LLC (US) 2025-10-15 — — EP claimed
EP-4580694-A1 SEALANTS FOR TISSUE CLOSURE Ethicon, Inc. (US) 2025-07-09 — — EP claimed
CN-115066232-A Compositions and methods for treating ocular diseases 视觉治疗股份有限公司 2022-09-16 — — CN claimed
US-20220218643-A1 COMPOSITIONS AND METHODS FOR TREATING OCULAR DISEASES BARINGS FINANCE LLC, AS AGENT 2022-07-14 — — US claimed
US-20220175672-A1 COMPOSITIONS AND METHODS FOR SUSTAINED DRUG RELEASE FROM AN INJECTABLE HYDROGEL CONTRALINE INC (US) 2022-06-09 — — US claimed
WO-2022103944-A1 HYDROGELS FORMED IN SITU AND COMPOSITION DESIGN FOR INTRAUTERINE USE Pramand LLC (US) 2022-05-19 — — WO claimed
US-20220143276-A1 HYDROGELS FORMED IN SITU AND COMPOSITION DESIGN FOR INTRAUTERINE USE Pramand LLC 2022-05-12 — — US claimed
WO-2022066891-A1 SUSTAINED RELEASE BIODEGRADABLE INTRACANALICULAR INSERTS COMPRISING A HYDROGEL AND AN ACTIVE AGENT OCULAR THERAPEUTIX, INC. (US) 2022-03-31 — — WO claimed
WO-2022066884-A1 SUSTAINED RELEASE BIODEGRADALBE INTRACANALICULAR INSERTS COMPRISING A HYDROGEL AND CYCLOSPORINE OCULAR THERAPEUTIX, INC. (US) 2022-03-31 — — WO claimed
EP-3973952-A1 SUSTAINED RELEASE BIODEGRADABLE INTRACANALICULAR INSERTS COMPRISING A HYDROGEL AND CYCLOSPORINE Ocular Therapeutix, Inc. (US) 2022-03-30 — — EP claimed
WO-2022060904-A1 COMPOSITIONS AND METHODS FOR EXPRESSION OF T-CELL RECEPTORS WITH SMALL MOLECULE-REGULATED CD40L IN T CELLS OBSIDIAN THERAPEUTICS, INC. (US) 2022-03-24 — — WO claimed
CN-112941044-A Novel gene for synergistically controlling plant yield and stress resistance traits and application thereof 中国科学院分子植物科学卓越创新中心 2021-06-11 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12599624-B2 Biodegradable lung sealants CD44, TTPA, PLOD3 LDHA 162/4885SNCA 4700/4885EPHX2 106/4885
US-20220218643-A1 COMPOSITIONS AND METHODS FOR TREATING OCULAR DISEASES PDE6C, PDE6H, PDE6A LDHA 2106/4885SNCA 3669/4885EPHX2 637/4885
US-20260035435-A1 APPROACHES FOR THE SELECTIVE DEPLETION OF PLA2R-SPECIFIC ANTIBODIES PLA2G2D, FCGR2A, PLA2R1 LDHA 3941/4885SNCA 4312/4885EPHX2 2618/4885
US-20260108634-A1 HIGH MOLECULAR WEIGHT MULTI-ARM POLYMERS AND MEDICAL HYDROGELS FORMED THEREFROM KIT, KLK3, CD44 LDHA 738/4885SNCA 4537/4885EPHX2 2066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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