Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15440257 | 1.00 | HTT (0.39) | HTTNPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL15440027 | 0.90 | HTT (0.48) | HTTNPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL15440029 | 0.90 | HTT (0.48) | HTTNPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL15438971 | 0.85 | SMN1; SMN2 (0.33) | HTTNPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL15438969 | 0.85 | SMN1; SMN2 (0.33) | HTTNPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL15438818 | 0.83 | HTT (0.38) | HTTNPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL15438820 | 0.83 | HTT (0.38) | HTTNPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL11873789 | 0.77 | GAA (0.41) | HTTNPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL11873794 | 0.77 | GAA (0.41) | HTTNPC1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL15439598 | 0.76 | ALDH1A1 (0.42) | HTTNPC1SMN1; SMN2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |