Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | G6PC1 | P35575 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439581 | 1.00 | ALDH1A1 (0.51) | ALDH1A1GAAALOX15MAPTTDP1 | |
| SCHEMBL15440335 | 0.87 | ALDH1A1 (0.50) | ALDH1A1GAAALOX15MAPTTDP1 | |
| SCHEMBL15440333 | 0.87 | ALDH1A1 (0.50) | ALDH1A1GAAALOX15MAPTTDP1 | |
| SCHEMBL15439911 | 0.84 | ALDH1A1 (0.47) | ALDH1A1GAAALOX15MAPTTDP1 | |
| SCHEMBL15440546 | 0.84 | ALDH1A1 (0.47) | ALDH1A1GAAALOX15MAPTTDP1 | |
| SCHEMBL15439912 | 0.84 | ALDH1A1 (0.47) | ALDH1A1GAAALOX15MAPTTDP1 | |
| SCHEMBL15438519 | 0.80 | G6PC1 (0.43) | ALDH1A1KMT2AG6PC1NPC1RAB9A | |
| SCHEMBL15438517 | 0.80 | G6PC1 (0.43) | ALDH1A1KMT2AG6PC1NPC1RAB9A | |
| SCHEMBL15440079 | 0.80 | G6PC1 (0.43) | ALDH1A1G6PC1NPC1RAB9A | |
| SCHEMBL15439402 | 0.75 | G6PC1 (0.49) | ALDH1A1GAAMAPTTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |