Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | G6PC1 | P35575 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15440372 | 0.94 | NPC1 (0.35) | NPC1RAB9ACA12CA9MEN1 | |
| SCHEMBL15440296 | 0.83 | G6PC1 (0.47) | NPC1RAB9ACA12CA9MEN1 | |
| SCHEMBL15440298 | 0.83 | G6PC1 (0.47) | NPC1RAB9ACA12CA9MEN1 | |
| SCHEMBL15438775 | 0.82 | NPC1 (0.44) | NPC1RAB9ACA12CA9MEN1 | |
| SCHEMBL15438772 | 0.82 | NPC1 (0.44) | NPC1RAB9ACA12CA9MEN1 | |
| SCHEMBL15440175 | 0.79 | NPC1 (0.38) | NPC1RAB9ACA12CA9MEN1 | |
| SCHEMBL15440173 | 0.79 | NPC1 (0.38) | NPC1RAB9ACA12CA9MEN1 | |
| SCHEMBL15440305 | 0.77 | G6PC1 (0.44) | NPC1RAB9ACA12CA9MEN1 | |
| SCHEMBL15440307 | 0.77 | G6PC1 (0.44) | NPC1RAB9ACA12CA9MEN1 | |
| SCHEMBL15438902 | 0.77 | PKM (0.35) | CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |