Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439738 | 1.00 | G6PC1 (0.40) | G6PC1ATMLMNATP53RAB9A | |
| SCHEMBL15440226 | 0.88 | MEN1 (0.41) | G6PC1LMNATP53RAB9ANPC1 | |
| SCHEMBL15440229 | 0.88 | MEN1 (0.41) | G6PC1LMNATP53RAB9ANPC1 | |
| SCHEMBL15439255 | 0.86 | G6PC1 (0.45) | G6PC1LMNARAB9ANPC1MAPT | |
| SCHEMBL15439254 | 0.86 | G6PC1 (0.45) | G6PC1LMNARAB9ANPC1MAPT | |
| SCHEMBL15439323 | 0.85 | G6PC1 (0.54) | G6PC1ATMLMNATP53RAB9A | |
| SCHEMBL15439321 | 0.85 | G6PC1 (0.54) | G6PC1ATMLMNATP53RAB9A | |
| SCHEMBL15439653 | 0.83 | RAB9A (0.44) | G6PC1ATMLMNATP53RAB9A | |
| SCHEMBL15439656 | 0.83 | RAB9A (0.44) | G6PC1ATMLMNATP53RAB9A | |
| SCHEMBL15439623 | 0.83 | NPC1 (0.41) | G6PC1LMNARAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |