Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439771 | 1.00 | KMT2A (0.46) | KMT2AHPGDMEN1CYP3A4MAPK1 | |
| SCHEMBL15439004 | 0.90 | NR4A2 (0.45) | KMT2AHPGDMEN1CYP3A4MAPK1 | |
| SCHEMBL15439006 | 0.90 | NR4A2 (0.45) | KMT2AHPGDMEN1CYP3A4MAPK1 | |
| SCHEMBL15440208 | 0.86 | MTNR1A (0.38) | KMT2AHPGDMEN1CYP3A4MAPK1 | |
| SCHEMBL15440211 | 0.86 | MTNR1A (0.38) | KMT2AHPGDMEN1CYP3A4MAPK1 | |
| SCHEMBL14799570 | 0.86 | ALDH1A1 (0.37) | KMT2AMEN1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL14799573 | 0.86 | ALDH1A1 (0.37) | KMT2AMEN1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL14799526 | 0.84 | ALDH1A1 (0.36) | KMT2AHPGDMEN1MAPK1MAPT | |
| SCHEMBL14799527 | 0.84 | ALDH1A1 (0.36) | KMT2AHPGDMEN1MAPK1MAPT | |
| SCHEMBL15440521 | 0.83 | SMN1; SMN2 (0.43) | KMT2AHPGDMEN1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |