Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15440419 | 0.88 | KMT2A (0.42) | ALDH1A1SMN1; SMN2MAPTRAB9ALMNA | |
| SCHEMBL15439933 | 0.86 | CYP1A2 (0.45) | ALDH1A1SMN1; SMN2MAPTRAB9ALMNA | |
| SCHEMBL15439931 | 0.84 | ATM (0.43) | ALDH1A1SMN1; SMN2MAPTRAB9ALMNA | |
| SCHEMBL15440575 | 0.83 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTRAB9ALMNA | |
| SCHEMBL15440260 | 0.83 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2MAPTRAB9ALMNA | |
| SCHEMBL15440368 | 0.81 | KMT2A (0.41) | ALDH1A1SMN1; SMN2MAPTRAB9ALMNA | |
| SCHEMBL15439754 | 0.79 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTRAB9ALMNA | |
| SCHEMBL15439756 | 0.79 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTRAB9ALMNA | |
| SCHEMBL15439399 | 0.79 | CYP1A2 (0.41) | ALDH1A1SMN1; SMN2MAPTRAB9ALMNA | |
| SCHEMBL15439967 | 0.79 | NR4A2 (0.49) | ALDH1A1SMN1; SMN2MAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |