Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439756 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL15439612 | 0.85 | KMT2A (0.50) | ALDH1A1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL15439610 | 0.85 | KMT2A (0.50) | ALDH1A1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL15440080 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL15440575 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL15440081 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL15439653 | 0.83 | RAB9A (0.44) | ALDH1A1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL15439656 | 0.83 | RAB9A (0.44) | ALDH1A1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL15440214 | 0.83 | CYP1A2 (0.44) | ALDH1A1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL15440215 | 0.83 | CYP1A2 (0.44) | ALDH1A1MAPTSMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |