Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15440214 | 1.00 | CYP1A2 (0.44) | CYP1A2CYP2D6HSD17B10MAPTALDH1A1 | |
| SCHEMBL15440036 | 0.84 | KMT2A (0.43) | CYP1A2CYP2D6HSD17B10MAPTALDH1A1 | |
| SCHEMBL15440037 | 0.84 | KMT2A (0.43) | CYP1A2CYP2D6HSD17B10MAPTALDH1A1 | |
| SCHEMBL14799202 | 0.84 | ATM (0.42) | CYP1A2CYP2D6HSD17B10MAPTALDH1A1 | |
| SCHEMBL14799201 | 0.84 | ATM (0.42) | CYP1A2CYP2D6HSD17B10MAPTALDH1A1 | |
| SCHEMBL15439996 | 0.83 | CYP1A2 (0.40) | CYP1A2CYP2D6HSD17B10MAPTALDH1A1 | |
| SCHEMBL15438712 | 0.83 | CYP1A2 (0.40) | CYP1A2CYP2D6HSD17B10MAPTALDH1A1 | |
| SCHEMBL15439994 | 0.83 | CYP1A2 (0.40) | CYP1A2CYP2D6HSD17B10MAPTALDH1A1 | |
| SCHEMBL15439754 | 0.83 | ALDH1A1 (0.48) | MAPTALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL15439756 | 0.83 | ALDH1A1 (0.48) | MAPTALDH1A1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |