Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14799631 | 0.88 | DEPTOR (0.39) | DEPTOR | |
| SCHEMBL15439370 | 0.83 | MEN1 (0.33) | MEN1USP2ALDH1A1LMNATP53 | |
| SCHEMBL15439902 | 0.83 | MEN1 (0.33) | MEN1USP2ALDH1A1LMNATP53 | |
| SCHEMBL15439975 | 0.81 | MEN1 (0.34) | MEN1USP2ALDH1A1LMNATP53 | |
| SCHEMBL15440034 | 0.76 | ALDH1A1 (0.35) | MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL9902097 | 0.74 | ALDH1A1 (0.60) | MEN1USP2ALDH1A1LMNATP53 | |
| SCHEMBL9899473 | 0.74 | ALDH1A1 (0.38) | MEN1USP2ALDH1A1LMNATP53 | |
| SCHEMBL9898050 | 0.70 | MEN1 (0.34) | MEN1USP2ALDH1A1LMNATP53 | |
| SCHEMBL15440315 | 0.70 | NR1H2 (0.32) | KMT2A | |
| SCHEMBL14799482 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |