SCHEMBL9899473

SCHEMBL9899473

CON=C1C=CC(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
LMNA P02545 3/20 0.38
MAPT P10636 3/20 0.38
MAPK1 P28482 2/20 0.38
MEN1 O00255 1/20 0.38
USP2 O75604 1/20 0.38
TP53 P04637 1/20 0.38
GLA P06280 1/20 0.38
CYP3A4 P08684 1/20 0.38
THRB P10828 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
BRCA1 P38398 1/20 0.38
BLM P54132 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ERBB2 P04626 1/20 0.31
PKM P14618 2/20 0.30
XBP1 P17861 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2044915 0.88
SCHEMBL9898050 0.81 MEN1 (0.34) ALDH1A1LMNAMAPTMAPK1MEN1
SCHEMBL9899257 0.80 MAPT (0.37) ALDH1A1LMNAMAPTMAPK1MEN1
SCHEMBL9902097 0.74 ALDH1A1 (0.60) ALDH1A1LMNAMAPTMAPK1MEN1
SCHEMBL15440225 0.74 MEN1 (0.38) ALDH1A1LMNAMAPTMAPK1MEN1
SCHEMBL9899204 0.72 MAOA (0.41) ALDH1A1LMNAMAPTKMT2APKM
SCHEMBL9898679 0.72 ALDH1A1 (0.33) ALDH1A1LMNAMAPTMAPK1MEN1
SCHEMBL9898820 0.72 MAPT (0.62) ALDH1A1LMNAMAPTMAPK1MEN1
SCHEMBL15439975 0.70 MEN1 (0.34) ALDH1A1LMNAMAPTMAPK1MEN1
SCHEMBL15439370 0.69 MEN1 (0.33) ALDH1A1LMNAMAPTMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US claimed
EP-2649102-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP Bridgestone Corporation (JP) 2013-10-16 EP claimed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
WO-2012078962-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 WO claimed
EP-2649102-B1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORP (JP) 2014-11-26 EP disclosed
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US disclosed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed