Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.41 |
| ▸ | FES | P07332 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | MARK3 | P27448 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2702269 | 0.85 | EPHX2 (0.57) | EPHX2FAAHSMN1; SMN2EPHX1FES | |
| SCHEMBL15440799 | 0.80 | EPHX2 (0.51) | EPHX2FAAHSMN1; SMN2EPHX1FES | |
| SCHEMBL19050209 | 0.79 | TSHR (0.54) | SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL23447431 | 0.78 | FBP1 (0.58) | EPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL24185375 | 0.78 | CYP2C9 (0.45) | SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL3421197 | 0.75 | EPHX2 (0.73) | EPHX2SMN1; SMN2EPHX1KEAP1NFE2L2 | |
| SCHEMBL8344039 | 0.74 | EPHX1 (0.51) | EPHX2EPHX1FESRETMARK3 | |
| SCHEMBL24587569 | 0.74 | TSHR (0.41) | SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL17905725 | 0.73 | EPHX2 (0.69) | EPHX2FAAHSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL22221566 | 0.72 | EPHX2 (0.71) | EPHX2FAAHSMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140024795-A1 | ALIPHATIC POLYCARBONATE POLYOLS CONTAINING SILYL GROUPS | NOVOMER, INC. (US) | 2014-01-23 | — | — | US | disclosed |