Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | FES | P07332 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | MARK3 | P27448 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2702269 | 0.94 | EPHX2 (0.57) | EPHX2SMN1; SMN2FESRETMARK3 | |
| SCHEMBL23447431 | 0.85 | FBP1 (0.58) | EPHX2SMN1; SMN2FBP1 | |
| SCHEMBL15440645 | 0.84 | PTPN1 (0.50) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3421197 | 0.83 | EPHX2 (0.73) | EPHX2SMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL1899410 | 0.82 | NPSR1 (0.57) | HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8344039 | 0.82 | EPHX1 (0.51) | EPHX2FESRETMARK3TYK2 | |
| SCHEMBL15440828 | 0.80 | EPHX2 (0.44) | EPHX2SMN1; SMN2FESRETMARK3 | |
| SCHEMBL13599779 | 0.79 | EPHX2 (0.68) | EPHX2FAAH | |
| SCHEMBL13039575 | 0.79 | HDAC1 (0.51) | HDAC3HDAC1HDAC2HDAC8 | |
| Urea SCHEMBL717178 | 0.79 | EPHX2 (0.67) | EPHX2SMN1; SMN2EPHX1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140024795-A1 | ALIPHATIC POLYCARBONATE POLYOLS CONTAINING SILYL GROUPS | NOVOMER, INC. (US) | 2014-01-23 | — | — | US | disclosed |