Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.64 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.64 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15440982 | 1.00 | HTR3A (0.64) | HTR3ACHRNB2CHRNA4 | |
| SCHEMBL15441283 | 0.90 | — | — | |
| SCHEMBL15447971 | 0.90 | — | — | |
| SCHEMBL15441350 | 0.90 | HTR3A (0.74) | HTR3ACHRNB2CHRNA4 | |
| SCHEMBL15441351 | 0.90 | HTR3A (0.74) | HTR3ACHRNB2CHRNA4 | |
| SCHEMBL13733192 | 0.86 | HTR3A (0.71) | HTR3ACHRNB2CHRNA4 | |
| SCHEMBL15441263 | 0.86 | HTR3A (0.71) | HTR3ACHRNB2CHRNA4 | |
| SCHEMBL13731607 | 0.85 | CHRNB2 (0.68) | HTR3ACHRNB2CHRNA4 | |
| SCHEMBL13731605 | 0.85 | CHRNB2 (0.68) | HTR3ACHRNB2CHRNA4 | |
| SCHEMBL15441031 | 0.81 | CHRNB2 (0.74) | HTR3ACHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10059704-B2 | 1,4-disubstituted 1,2,3-triazoles, methods for preparing same, and diagnostic and therapeutic uses thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2018-08-28 | — | — | US | disclosed |
| EP-2699570-B1 | 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES, THEIR PREPARATION PROCESSES AND THEIR DIAGNOSTIC AND THERAPEUTIC USES | CENTRE NAT RECH SCIENT (FR) | 2018-08-22 | — | — | EP | disclosed |
| US-20140030191-A1 | 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES, METHODS FOR PREPARING SAME, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2014-01-30 | — | — | US | disclosed |
| US-20140030191-A1 | 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES, METHODS FOR PREPARING SAME, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2014-01-30 | — | — | US | disclosed |
| US-20140030191-A1 | 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES, METHODS FOR PREPARING SAME, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2014-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140030191-A1 | 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES, METHODS FOR PREPARING SAME, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF | CYP3A43, NAT1, UGT1A1 | HTR3A 206/4885CHRNB2 1237/4885CHRNA4 1279/4885 |
| US-10059704-B2 | 1,4-disubstituted 1,2,3-triazoles, methods for preparing same, and diagnostic and therapeutic uses thereof | CYP3A43, NAT1, UGT1A1 | HTR3A 206/4885CHRNB2 1237/4885CHRNA4 1279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.