Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.44 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.44 |
| ▸ | LGALS4 | P56470 | 2/20 | 0.44 |
| ▸ | GBA1 | P04062 | 2/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14747620 | 0.92 | MAPK1 (0.52) | GJB2MAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL18733415 | 0.87 | MAPK1 (0.48) | GJB2MAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL5678760 | 0.87 | MAPK1 (0.58) | GJB2MAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL14413981 | 0.87 | MAPK1 (0.51) | GJB2MAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL17300176 | 0.87 | MAPK1 (0.44) | GJB2MAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL16079127 | 0.87 | MAPK1 (0.44) | GJB2MAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL18733215 | 0.87 | MAPK1 (0.44) | GJB2MAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL12819629 | 0.87 | MAPK1 (0.44) | GJB2MAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL15508089 | 0.87 | MAPK1 (0.44) | GJB2MAPK1LGALS8LGALS3LGALS4 | |
| SCHEMBL18733408 | 0.87 | MAPK1 (0.44) | GJB2MAPK1LGALS8LGALS3LGALS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637578-B2 | Reagents and methods for the formation of disulfide bonds and the glycosylation of proteins | ISIS INNOVATION LIMITED (GB) | 2014-01-28 | — | — | US | disclosed |