Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 8/20 | 0.36 |
| ▸ | FGF1 | P05230 | 6/20 | 0.36 |
| ▸ | FGF2 | P09038 | 6/20 | 0.36 |
| ▸ | VEGFA | P15692 | 3/20 | 0.36 |
| ▸ | F11 | P03951 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445115 | 0.84 | MAPK1 (0.37) | HPSEFGF1FGF2VEGFAMAPK1 | |
| SCHEMBL15492489 | 0.83 | MAPK1 (0.40) | HPSEFGF1FGF2VEGFAMAPK1 | |
| SCHEMBL17817123 | 0.82 | HPSE (0.38) | HPSEFGF1FGF2VEGFAF11 | |
| SCHEMBL15747286 | 0.81 | GJB2 (0.40) | HPSEFGF1FGF2VEGFAMAPK1 | |
| SCHEMBL6223743 | 0.80 | CYP2D6 (0.36) | HPSEFGF1FGF2VEGFAF11 | |
| SCHEMBL6223748 | 0.80 | CYP2D6 (0.36) | HPSEFGF1FGF2VEGFAF11 | |
| SCHEMBL17445205 | 0.79 | MAPK1 (0.37) | HPSEFGF1FGF2VEGFAMAPK1 | |
| SCHEMBL6553262 | 0.79 | SSTR1 (0.44) | CYP2D6MAPK1 | |
| SCHEMBL6553266 | 0.79 | SSTR1 (0.44) | CYP2D6MAPK1 | |
| SCHEMBL19479699 | 0.79 | TNF (0.42) | HPSEFGF1FGF2VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637578-B2 | Reagents and methods for the formation of disulfide bonds and the glycosylation of proteins | ISIS INNOVATION LIMITED (GB) | 2014-01-28 | — | — | US | disclosed |