Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | IGF2R | P11717 | 4/20 | 0.36 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | SELP | P16109 | 1/20 | 0.32 |
| ▸ | FGF1 | P05230 | 3/20 | 0.32 |
| ▸ | FGF2 | P09038 | 3/20 | 0.32 |
| ▸ | VEGFA | P15692 | 3/20 | 0.32 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16327920 | 0.85 | LGALS8 (0.39) | TLR4LGALS8 | |
| SCHEMBL15445116 | 0.84 | HPSE (0.36) | MAPK1FGF1FGF2VEGFAHPSE | |
| SCHEMBL27953839 | 0.84 | LGALS8 (0.36) | TLR4LGALS8 | |
| SCHEMBL15492489 | 0.82 | MAPK1 (0.40) | MAPK1IGF2RLGALS8SELPFGF1 | |
| SCHEMBL17784276 | 0.81 | LGALS8 (0.33) | LGALS8 | |
| SCHEMBL16327913 | 0.79 | F11 (0.37) | MAPK1TLR4LGALS8 | |
| SCHEMBL17445205 | 0.78 | MAPK1 (0.37) | MAPK1LGALS8SELPFGF1FGF2 | |
| SCHEMBL27857131 | 0.78 | MAPT (0.35) | MAPK1LGALS8 | |
| SCHEMBL19877291 | 0.78 | MAPT (0.33) | LGALS8 | |
| SCHEMBL2629592 | 0.77 | LGALS8 (0.48) | MAPK1LGALS8FGF1FGF2VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637578-B2 | Reagents and methods for the formation of disulfide bonds and the glycosylation of proteins | ISIS INNOVATION LIMITED (GB) | 2014-01-28 | — | — | US | disclosed |