Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445450 | 0.83 | ALDH1A1 (0.69) | ALDH1A1EGLN1 | |
| SCHEMBL13943232 | 0.82 | ALDH1A1 (0.54) | ALDH1A1EGLN1LMNAKDM4EMAPT | |
| SCHEMBL644794 | 0.82 | ALDH1A1 (0.68) | ALDH1A1EGLN1LMNAKDM4EMAPT | |
| SCHEMBL3502575 | 0.78 | KDM4E (0.56) | ALDH1A1EGLN1LMNAKDM4EHTT | |
| SCHEMBL23714060 | 0.78 | EGLN1 (0.56) | ALDH1A1EGLN1KDRNPC1CASP3 | |
| SCHEMBL14136247 | 0.77 | ALDH1A1 (0.49) | ALDH1A1EGLN1LMNAKDM4EMAPT | |
| SCHEMBL9983599 | 0.77 | ALDH1A1 (0.49) | ALDH1A1EGLN1LMNAKDM4EMAPT | |
| SCHEMBL18069879 | 0.77 | ALDH1A1 (0.49) | ALDH1A1EGLN1KDM4EMAPTHTT | |
| SCHEMBL643192 | 0.74 | ALDH1A1 (0.46) | ALDH1A1EGLN1LMNAKDM4EMAPT | |
| SCHEMBL13065799 | 0.73 | KDM4E (0.52) | ALDH1A1LMNAKDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140031355-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | AMGEN INC. (US) | 2014-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031355-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | MCL1, SSB, MALT1 | ALDH1A1 3702/4885EGLN1 2256/4885LMNA 2393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.