Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12647755 | 0.86 | ALDH1A1 (0.67) | ALDH1A1EGLN1 | |
| SCHEMBL27872555 | 0.83 | ALDH1A1 (0.77) | ALDH1A1EGLN1 | |
| SCHEMBL15445449 | 0.83 | ALDH1A1 (0.50) | ALDH1A1EGLN1 | |
| SCHEMBL1759043 | 0.81 | ALDH1A1 (1.00) | ALDH1A1EGLN1 | |
| SCHEMBL253460 | 0.80 | ALDH1A1 (0.73) | ALDH1A1EGLN1 | |
| SCHEMBL9139640 | 0.80 | ALDH1A1 (0.97) | ALDH1A1EGLN1 | |
| SCHEMBL2143864 | 0.80 | ALDH1A1 (0.73) | ALDH1A1EGLN1 | |
| SCHEMBL2143721 | 0.80 | ALDH1A1 (0.73) | ALDH1A1EGLN1 | |
| SCHEMBL8885906 | 0.80 | ALDH1A1 (0.73) | ALDH1A1EGLN1 | |
| SCHEMBL7969418 | 0.80 | ALDH1A1 (0.58) | ALDH1A1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140031355-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | AMGEN INC. (US) | 2014-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031355-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | MCL1, SSB, MALT1 | ALDH1A1 3702/4885EGLN1 2256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.