SCHEMBL15445504

SCHEMBL15445504

Cc1ccc([Si](C)(O)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.47
TDP1 Q9NUW8 1/20 0.47
ALDH1A1 P00352 6/20 0.38
LMNA P02545 3/20 0.38
CA2 P00918 2/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
LPL P06858 1/20 0.38
LIPG Q9Y5X9 1/20 0.38
ORAI1 Q96D31 1/20 0.38
ORAI2 Q96SN7 1/20 0.38
ORAI3 Q9BRQ5 1/20 0.38
TRPV6 Q9H1D0 1/20 0.38
CA1 P00915 2/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
TSHR P16473 4/20 0.35
HPGD P15428 2/20 0.33
NOTUM Q6P988 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272363 0.87 ESR1 (0.38) HPGD
SCHEMBL3482615 0.82 ACHE (0.47) ACHETDP1ALDH1A1LMNACA2
SCHEMBL1054613 0.81 ACHE (0.53) ACHETDP1ALDH1A1LMNACA2
SCHEMBL6433024 0.79 ESR1 (0.35) HPGD
SCHEMBL7862066 0.79 ACHE (0.50) ACHETDP1ALDH1A1LMNACA2
SCHEMBL1686464 0.79 ACHE (0.50) ACHETDP1ALDH1A1LMNACA2
SCHEMBL1686889 0.79 ACHE (0.50) ACHETDP1ALDH1A1LMNACA2
SCHEMBL9220040 0.75 ACHE (0.53) ACHETDP1ALDH1A1LMNACA2
SCHEMBL4569584 0.75 ACHE (0.53) ACHETDP1ALDH1A1LMNACA2
SCHEMBL987122 0.75 ACHE (0.53) ACHETDP1ALDH1A1LMNACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9365694-B2 Composition including polyimide block copolymer and inorganic particles, method of preparing same, article including same, and display device including the article SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-14 US disclosed
US-20140031499-A1 COMPOSITION INCLUDING POLYIMIDE BLOCK COPOLYMER AND INORGANIC PARTICLES, METHOD OF PREPARING SAME, ARTICLE INCLUDING SAME, AND DISPLAY DEVICE INCLUDING THE ARTICLE SAMSUNG ELECTRONICS CO., LTD. (KR) 2014-01-30 US disclosed