Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13824178 | 0.91 | TP53 (0.33) | HTTTP53 | |
| SCHEMBL15470691 | 0.90 | HTT (0.32) | HTTTP53 | |
| SCHEMBL13824173 | 0.90 | HTT (0.33) | HTT | |
| SCHEMBL15470692 | 0.89 | HTT (0.32) | HTTTP53 | |
| SCHEMBL15445493 | 0.88 | PDK2 (0.31) | HTTTP53 | |
| SCHEMBL15445521 | 0.88 | HTT (0.32) | HTTTP53 | |
| SCHEMBL15470689 | 0.88 | PDK2 (0.34) | HTTTDP1TP53 | |
| SCHEMBL14233227 | 0.88 | HTT (0.33) | HTT | |
| SCHEMBL22239340 | 0.87 | ALK (0.32) | HTT | |
| SCHEMBL17479893 | 0.87 | HTT (0.31) | HTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9250356-B2 | Photochromic polymers | VIVIMED LABS EUROPE LTD (GB) | 2016-02-02 | — | — | US | disclosed |
| US-9250356-B2 | Photochromic polymers | VIVIMED LABS EUROPE LTD (GB) | 2016-02-02 | — | — | US | disclosed |
| US-20140027684-A1 | PHOTOCHROMIC POLYMERS | VIVIMED LABS EUROPE LTD (GB) | 2014-01-30 | — | — | US | disclosed |
| US-20140027684-A1 | PHOTOCHROMIC POLYMERS | VIVIMED LABS EUROPE LTD (GB) | 2014-01-30 | — | — | US | disclosed |