Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | PPARG | P37231 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20230373 | 0.94 | PPARG (0.68) | TSHRPPARGKDM4ERAB9AMAPT | |
| SCHEMBL10359783 | 0.94 | PPARG (0.67) | TSHRPPARGKDM4ERAB9AMAPT | |
| SCHEMBL7827993 | 0.90 | TSHR (0.71) | TSHRPPARGKDM4ERAB9AMAPT | |
| SCHEMBL9888805 | 0.85 | TSHR (0.79) | TSHRPPARGKDM4ERAB9AMAPT | |
| SCHEMBL18997859 | 0.85 | HPGD (0.56) | TSHRPPARGKDM4ERAB9AMAPT | |
| SCHEMBL11978602 | 0.85 | PPARG (0.55) | TSHRPPARGKDM4ERAB9AMAPT | |
| SCHEMBL8150945 | 0.84 | TSHR (0.71) | TSHRPPARGKDM4EMAPTL3MBTL1 | |
| SCHEMBL8156820 | 0.84 | TSHR (0.71) | TSHRPPARGKDM4EMAPTL3MBTL1 | |
| SCHEMBL3161533 | 0.83 | TSHR (1.00) | TSHRPPARGKDM4ERAB9AL3MBTL1 | |
| SCHEMBL116448 | 0.83 | RAB9A (0.78) | TSHRKDM4ERAB9AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912120-B2 | Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid or a derivative thereof and synthetic auxin herbicides | DOW AGROSCIENCES, LLC. (US) | 2014-12-16 | — | — | US | disclosed |
| US-20140031214-A1 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND SYNTHETIC AUXIN HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031214-A1 | HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND SYNTHETIC AUXIN HERBICIDES | DDT, HPD, P4HTM | TSHR 1251/4885PPARG 323/4885KDM4E 529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.