SCHEMBL15445817

SCHEMBL15445817

CCCC1CCC(C2CCC(COc3ccc(OC)c(F)c3F)CC2)CC1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 15/20 0.38
RIPK1 Q13546 1/20 0.38
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
SGPL1 O95470 1/20 0.36
S1PR1 P21453 1/20 0.36
HTR2A P28223 2/20 0.35
HTR2C P28335 2/20 0.35
HTR2B P41595 2/20 0.35
PDE4A P27815 4/20 0.35
PDE4C Q08493 4/20 0.35
PDE4D Q08499 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9562683 1.00 PDE4B (0.38) PDE4BRIPK1ALDH1A1MAPTHTT
SCHEMBL9562689 1.00 PDE4B (0.38) PDE4BRIPK1ALDH1A1MAPTHTT
SCHEMBL9562677 1.00 PDE4B (0.38) PDE4BRIPK1ALDH1A1MAPTHTT
SCHEMBL29432432 0.96 PDE4B (0.40) PDE4BRIPK1ALDH1A1MAPTHTT
SCHEMBL29364960 0.96 PDE4B (0.40) PDE4BRIPK1ALDH1A1MAPTHTT
SCHEMBL19460282 0.96 PDE4B (0.40) PDE4BRIPK1ALDH1A1MAPTHTT
SCHEMBL13528234 0.96 PDE4B (0.40) PDE4BRIPK1ALDH1A1MAPTHTT
SCHEMBL24170502 0.94 RIPK1 (0.41) PDE4BRIPK1ALDH1A1MAPTHTT
SCHEMBL9924821 0.92 PDE4B (0.35) PDE4BALDH1A1MAPTHTTSGPL1
SCHEMBL9924783 0.92 SCN9A (0.36) PDE4BRIPK1ALDH1A1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9777220-B2 Polymerizable compound-containing liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2017-10-03 US disclosed
US-9777220-B2 Polymerizable compound-containing liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2017-10-03 US disclosed
EP-2808376-B1 METHOD FOR PRODUCING COMPOSITION DAINIPPON INK & CHEMICALS (JP) 2017-09-20 EP disclosed
US-20170210989-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2017-07-27 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
EP-2952554-B1 POLYMERIZABLE COMPOUND-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DAINIPPON INK & CHEMICALS (JP) 2017-03-01 EP disclosed
US-20160274418-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2016-09-22 US disclosed
US-9441159-B2 Method for producing composition DIC CORPORATION (JP) 2016-09-13 US disclosed
US-9441159-B2 Method for producing composition DIC CORPORATION (JP) 2016-09-13 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
EP-2743331-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC Corporation (JP) 2014-06-18 EP disclosed
US-20140154428-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-06-05 US disclosed
US-20140121345-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-05-01 US disclosed
US-20140070142-A1 NEMATIC LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2014-03-13 US disclosed
US-20140070142-A1 NEMATIC LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2014-03-13 US disclosed
US-20140028964-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2014-01-30 US disclosed
EP-2657318-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND, AND LIQUID CRYSTAL DISPLAY ELEMENT UTILIZING SAME DIC Corporation (JP) 2013-10-30 EP disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed