Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 15/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 4/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562683 | 1.00 | PDE4B (0.38) | PDE4BRIPK1ALDH1A1MAPTHTT | |
| SCHEMBL15445817 | 1.00 | PDE4B (0.38) | PDE4BRIPK1ALDH1A1MAPTHTT | |
| SCHEMBL9562677 | 1.00 | PDE4B (0.38) | PDE4BRIPK1ALDH1A1MAPTHTT | |
| SCHEMBL29432432 | 0.96 | PDE4B (0.40) | PDE4BRIPK1ALDH1A1MAPTHTT | |
| SCHEMBL29364960 | 0.96 | PDE4B (0.40) | PDE4BRIPK1ALDH1A1MAPTHTT | |
| SCHEMBL19460282 | 0.96 | PDE4B (0.40) | PDE4BRIPK1ALDH1A1MAPTHTT | |
| SCHEMBL13528234 | 0.96 | PDE4B (0.40) | PDE4BRIPK1ALDH1A1MAPTHTT | |
| SCHEMBL24170502 | 0.94 | RIPK1 (0.41) | PDE4BRIPK1ALDH1A1MAPTHTT | |
| SCHEMBL9924821 | 0.92 | PDE4B (0.35) | PDE4BALDH1A1MAPTHTTSGPL1 | |
| SCHEMBL9924783 | 0.92 | SCN9A (0.36) | PDE4BRIPK1ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248447-A | 2,3-difluorohydroquinone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-28 | — | — | US | disclosed |