SCHEMBL15457926

SCHEMBL15457926

Brc1ccc(-c2ccccc2)c2c(-c3ccccc3)cccc12

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.58
CYP1B1 Q16678 15/20 0.53
ALDH1A1 P00352 3/20 0.52
MAPK1 P28482 1/20 0.52
POLB P06746 2/20 0.45
RXFP1 Q9HBX9 1/20 0.45
HKDC1 Q2TB90 1/20 0.43
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
PABPC1 P11940 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13002347 0.90 CYP1A2 (0.53) CYP1A2CYP1B1ALDH1A1MAPK1POLB
SCHEMBL20259109 0.89 CYP1A2 (0.51) CYP1A2CYP1B1ALDH1A1MAPK1POLB
SCHEMBL21368134 0.86 CYP1A2 (0.53) CYP1A2CYP1B1ALDH1A1MAPK1POLB
SCHEMBL24945277 0.86 ALDH1A1 (0.50) CYP1A2CYP1B1ALDH1A1MAPK1HKDC1
SCHEMBL30170061 0.85 CYP1A2 (0.51) CYP1A2CYP1B1ALDH1A1MAPK1POLB
SCHEMBL959783 0.85 CYP1A2 (0.51) CYP1A2CYP1B1ALDH1A1MAPK1POLB
SCHEMBL22717171 0.85 CYP1A2 (0.44) CYP1A2CYP1B1ALDH1A1MAPK1POLB
SCHEMBL18859286 0.85 ALDH1A1 (0.45) CYP1A2CYP1B1ALDH1A1MAPK1POLB
SCHEMBL663504 0.85 CYP1A2 (0.63) CYP1A2CYP1B1ALDH1A1MAPK1POLB
SCHEMBL30345509 0.85 CYP1A2 (0.63) CYP1A2CYP1B1ALDH1A1MAPK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9024304-B2 Naphthalene derivative, organic material including the same, and organic electroluminescent device including the same DAE JOO ELECTRONIC MATERIALS CO., LTD. (KR) 2015-05-05 US disclosed
US-9024304-B2 Naphthalene derivative, organic material including the same, and organic electroluminescent device including the same DAE JOO ELECTRONIC MATERIALS CO., LTD. (KR) 2015-05-05 US disclosed
US-20140299849-A1 NAPHTHALENE DERIVATIVE, ORGANIC MATERIAL INCLUDING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME DAE JOO ELECTRONIC MATERIALS CO., LTD. (KR) 2014-10-09 US disclosed
US-20140299849-A1 NAPHTHALENE DERIVATIVE, ORGANIC MATERIAL INCLUDING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME DAE JOO ELECTRONIC MATERIALS CO., LTD. (KR) 2014-10-09 US disclosed
EP-2692823-A2 NAPHTHALENE DERIVATIVES, ORGANIC MATERIAL USING SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME Dae Joo Electronic Materials Co., Ltd. (KR) 2014-02-05 EP disclosed