SCHEMBL24945277

SCHEMBL24945277

Brc1ccc(-c2ccccc2)c2cccc(-c3ccccc3)c12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
MAPK1 P28482 1/20 0.50
CYP1A2 P05177 1/20 0.43
CYP1B1 Q16678 5/20 0.41
LIMK1 P53667 2/20 0.38
CLK4 Q9HAZ1 2/20 0.38
PLK4 O00444 1/20 0.38
MAPK9 P45984 1/20 0.38
AKT3 Q9Y243 1/20 0.38
METAP2 P50579 1/20 0.38
HKDC1 Q2TB90 1/20 0.38
TNF P01375 1/20 0.38
PARP1 P09874 1/20 0.37
MAP4K4 O95819 1/20 0.37
CSF1R P07333 1/20 0.37
FGFR1 P11362 1/20 0.37
PDGFRA P16234 1/20 0.37
LTK P29376 1/20 0.37
KDR P35968 1/20 0.37
MAPK8 P45983 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22727730 0.90 ALDH1A1 (0.52) ALDH1A1MAPK1CYP1A2CYP1B1LIMK1
SCHEMBL15457926 0.86 CYP1A2 (0.58) ALDH1A1MAPK1CYP1A2CYP1B1HKDC1
SCHEMBL22727733 0.85 ALDH1A1 (0.52) ALDH1A1MAPK1CYP1A2CYP1B1LIMK1
SCHEMBL29309945 0.83 CYP2A6 (0.45) ALDH1A1MAPK1CYP1A2CYP1B1LIMK1
SCHEMBL2162977 0.81 ALDH1A1 (0.54) ALDH1A1MAPK1CYP1A2CYP1B1PARP1
SCHEMBL28636970 0.79 ALDH1A1 (0.54) ALDH1A1MAPK1CYP1A2LIMK1CLK4
SCHEMBL31107072 0.79 CRHBP (0.56) ALDH1A1MAPK1CYP1A2LIMK1CLK4
SCHEMBL2033903 0.79 CRHBP (0.56) ALDH1A1MAPK1CYP1A2LIMK1CLK4
SCHEMBL20033065 0.79 ALDH1A1 (0.65) ALDH1A1MAPK1CYP1A2LIMK1CLK4
SCHEMBL28668358 0.79 ALDH1A1 (0.52) ALDH1A1MAPK1CYP1A2CYP1B1PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230013038-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-01-19 US disclosed