SCHEMBL15460240

SCHEMBL15460240

CC1(C)c2ccccc2-c2cc3c(-c4cccc5c4sc4ccccc45)cc4oc5cc(-c6cccc7c6sc6ccccc67)c6cc7c(cc6c5c4c3cc21)C(C)(C)c1ccccc1-7

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.40
PRKDC P78527 9/20 0.39
PARP14 Q460N5 1/20 0.38
PIK3CD O00329 2/20 0.36
PIK3CB P42338 2/20 0.36
BRD4 O60885 1/20 0.36
PIK3CA P42336 1/20 0.36
MTOR P42345 1/20 0.36
PIK3CG P48736 1/20 0.36
KCNH2 Q12809 1/20 0.36
BRDT Q58F21 1/20 0.36
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
HTT P42858 1/20 0.31
PAX8 Q06710 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15460318 0.89 ALOX5 (0.41) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL15460204 0.89 ALOX5 (0.41) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL15460279 0.87 ALOX5 (0.44) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL14725798 0.85 ALOX5 (0.42) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL15460246 0.82 PRKDC (0.33) PRKDC
SCHEMBL15460222 0.80 ALOX5 (0.50) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL17206428 0.78 ALOX5 (0.51) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL16202888 0.78 ALOX5 (0.38) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL17886447 0.77 PARP14 (0.45) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL15460250 0.76 ALOX5 (0.45) ALOX5PRKDCPARP14PIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed