SCHEMBL15460246

SCHEMBL15460246

CC1(C)c2ccccc2-c2cc3c(-c4csc5ccccc45)cc4oc5cc(-c6csc7ccccc67)c6cc7c(cc6c5c4c3cc21)C(C)(C)c1ccccc1-7

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 2/20 0.33
APP P05067 2/20 0.32
MAOB P27338 1/20 0.32
CYP2C9 P11712 1/20 0.31
ATM Q13315 1/20 0.31
KDM1A O60341 1/20 0.31
ERN1 O75460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15460198 0.88 PRKDC (0.36) PRKDCAPPMAOBCYP2C9ATM
SCHEMBL15460329 0.87 MAPT (0.33) APPMAOBCYP2C9KDM1AERN1
SCHEMBL15460282 0.84 APP (0.33) PRKDCAPPMAOBCYP2C9KDM1A
SCHEMBL14725781 0.83 APP (0.33) PRKDCAPPMAOBCYP2C9KDM1A
SCHEMBL21180630 0.83 PGR (0.34)
SCHEMBL15460240 0.82 ALOX5 (0.40) PRKDC
SCHEMBL15460249 0.78 PRKDC (0.40) PRKDCAPPMAOBCYP2C9ATM
SCHEMBL15460237 0.75 MAPT (0.38)
SCHEMBL15460241 0.74 AHR (0.41) PRKDCAPPMAOBCYP2C9ATM
SCHEMBL15460232 0.73 PRKDC (0.39) PRKDCAPPMAOBCYP2C9ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed