SCHEMBL15460291

SCHEMBL15460291

c1ccc(-n2c3ccccc3c3cc4c(cc32)c(-c2cccnc2)cc2c3cc(-c5cccnc5)c5cc6c(cc5c3sc42)c2ccccc2n6-c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
MAPT P10636 3/20 0.38
ALDH1A1 P00352 2/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
CYP1A2 P05177 2/20 0.37
METAP2 P50579 1/20 0.37
POLB P06746 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
CYP2A6 P11509 1/20 0.36
CYP11B2 P19099 1/20 0.36
GAA P10253 1/20 0.36
MAPK14 Q16539 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
GPR84 Q9NQS5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15460210 0.86 CYP11B1 (0.42) CYP11B1L3MBTL1KDM4EATMMAPT
SCHEMBL15461875 0.85 CYP11B1 (0.49) CYP11B1L3MBTL1KDM4EATMMAPT
SCHEMBL15912237 0.85 CYP11B1 (0.49) CYP11B1L3MBTL1KDM4EATMMAPT
SCHEMBL14725692 0.85 CYP11B1 (0.49) CYP11B1L3MBTL1KDM4EATMMAPT
SCHEMBL15460292 0.83 L3MBTL1 (0.47) L3MBTL1KDM4EATMMAPTALDH1A1
SCHEMBL15912270 0.82 CYP11B1 (0.55) CYP11B1L3MBTL1KDM4EATMMAPT
SCHEMBL16472899 0.82 CYP11B1 (0.42) CYP11B1L3MBTL1KDM4EATMMAPT
SCHEMBL16472895 0.82 CYP11B1 (0.42) CYP11B1L3MBTL1KDM4EATMMAPT
SCHEMBL15912273 0.80 CYP11B1 (0.49) CYP11B1L3MBTL1KDM4EATMMAPT
SCHEMBL14725683 0.80 CYP11B1 (0.43) CYP11B1L3MBTL1KDM4EATMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed