Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.74 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.74 |
| ▸ | TUBB | P07437 | 2/20 | 0.74 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.74 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.74 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.74 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.74 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.74 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.74 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.74 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.74 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.74 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.74 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.74 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.74 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2329685 | 0.85 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2329679 | 0.85 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30504103 | 0.85 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL25196076 | 0.85 | TUBB1 (0.79) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30384079 | 0.85 | TUBB1 (0.79) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL15460399 | 0.84 | ABCG2 (0.55) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL25196870 | 0.83 | CXCL12 (0.80) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3195246 | 0.83 | CALM1 (0.88) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL25230917 | 0.83 | CXCL12 (0.80) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL31233041 | 0.83 | CXCL12 (0.80) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102638-B2 | Amidobenzothiazoles and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-08-11 | — | — | US | disclosed |
| US-8921552-B2 | Benzothiazole hybrids useful as anticancer agents and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-12-30 | — | — | US | disclosed |
| US-20140039190-A1 | BENZOTHIAZOLE HYBRIDS USEFUL AS ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140039190-A1 | BENZOTHIAZOLE HYBRIDS USEFUL AS ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | TP53, MCL1, SDHA | TUBB1 105/4885TUBB4A 40/4885TUBB 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.